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Beilstein J. Org. Chem. 2008, 4, No. 26, doi:10.3762/bjoc.4.26
Graphical Abstract
Figure 1: The two general synthetic approaches to oxazolo[5,4-d]pyrimidines.
Figure 2: Thermal cyclodehydration route to 9-oxo-guanine.
Figure 3: Preparation of 2-substituted 5-aminooxazolo[5,4-d]pyrimidin-7(6H)-ones.
Figure 4: Preparation of 2-substituted 5-aminooxazolo[5,4-d]pyrimidin-7(6H)-ones and related thioethers.
Figure 5: Click chemistry elaboration of a 5-(propargylthio)oxazolo[5,4-d]pyrimidine.